SCOPe 2.06: Domain d2v10o_: 2v10 O:

Lineage for d2v10o_ (2v10 O:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (76 PDB entries)

8. Domain d2v10o_: 2v10 O: [243832]
   automated match to d3g72b_
   complexed with c61

Details for d2v10o_

PDB Entry: 2v10, 3.1 Å

PDB Description: crystal structure of renin with inhibitor 9

PDB Compounds: (O:) renin

SCOPe Domain Sequences for d2v10o_:

Sequence, based on SEQRES records:

>d2v10o_ b.50.1.2 (O:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggsdpq
hyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklme
algakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamd
ippptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d2v10o_ b.50.1.2 (O:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
nttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyhklf
dasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfmlaef
dgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsslggqivlggsdpqhyeg
nfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmealga
kkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdippp
tgptwalgatfirkfytefdrrnnrigfalar

Timeline for d2v10o_:

• d2v10o_ first appeared in SCOPe 2.04
  
• d2v10o_ appears in SCOPe 2.05
  
• d2v10o_ appears in SCOPe 2.07
  
• d2v10o_ appears in the current release, SCOPe 2.08