SCOPe 2.05: Domain d2pvsa1: 2pvs A:-2-336

Lineage for d2pvsa1 (2pvs A:-2-336)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.19: Pancreatic lipase, N-terminal domain [53577] (2 proteins)
   automatically mapped to Pfam PF00151

6. Protein automated matches [226890] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225244] (3 PDB entries)

8. Domain d2pvsa1: 2pvs A:-2-336 [243500]
   Other proteins in same PDB: d2pvsa2, d2pvsb2
   automated match to d2oxea1
   complexed with ca, so4; mutant

Details for d2pvsa1

PDB Entry: 2pvs, 3 Å

PDB Description: structure of human pancreatic lipase related protein 2 mutant n336q

PDB Compounds: (A:) Pancreatic lipase-related protein 2

SCOPe Domain Sequences for d2pvsa1:

Sequence, based on SEQRES records:

>d2pvsa1 c.69.1.19 (A:-2-336) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
knvlstitdidgiwegiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfp
cpaegcpkmghyadqfkgktsaveqtfflntgesgqft

Sequence, based on observed residues (ATOM records):

>d2pvsa1 c.69.1.19 (A:-2-336) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kevcygqlgcfsdekpwagtlqrpvkllpwspedidtrfllytnenpnnfqlitgtepdt
ieasnfqldrktrfiihgfldkaedswpsdmckkmfevekvncicvdwrhgsramytqav
qnirvvgaetafliqalstqlgysledvhvighslgahtaaeagrrlggrvgritgldpa
gpcfqdepeevrldpsdavfvdvihtdsspivpslgfgmsqkvghldffpnggkempgck
egiggfvscnhlrsfeyysssvlnpdgflgypcasydefqeskcfpcpaegcpkmghyad
qfkgktsaveqtfflntgesgqft

Timeline for d2pvsa1:

• d2pvsa1 first appeared in SCOPe 2.04
  
• d2pvsa1 appears in SCOPe 2.06
  
• d2pvsa1 appears in the current release, SCOPe 2.08