SCOPe 2.08: Domain d2ouub1: 2ouu B:449-768

Lineage for d2ouub1 (2ouu B:449-768)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d2ouub1: 2ouu B:449-768 [243389]
   Other proteins in same PDB: d2ouua2, d2ouub2
   automated match to d2ourb_
   complexed with 35g, mg; mutant

Details for d2ouub1

PDB Entry: 2ouu, 1.52 Å

PDB Description: crystal structure of pde10a2 mutant d674a in complex with cgmp

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d2ouub1:

Sequence, based on SEQRES records:

>d2ouub1 a.211.1.0 (B:449-768) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirg

Sequence, based on observed residues (ATOM records):

>d2ouub1 a.211.1.0 (B:449-768) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyf
gnrkqleemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtkltandiyaefwae
gdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnl
sqwekvirg

Timeline for d2ouub1:

• d2ouub1 first appeared in SCOPe 2.04, called d2ouub_
  
• d2ouub1 appears in SCOPe 2.07