SCOPe 2.05: Domain d2ouqb_: 2ouq B:

Lineage for d2ouqb_ (2ouq B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (86 PDB entries)

8. Domain d2ouqb_: 2ouq B: [243385]
   automated match to d2ouna_
   complexed with 5gp, mg, zn

Details for d2ouqb_

PDB Entry: 2ouq, 1.9 Å

PDB Description: crystal structure of PDE10A2 in complex with GMP

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d2ouqb_:

Sequence, based on SEQRES records:

>d2ouqb_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
shmsictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfel
eklcrfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdl
dhrgfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvlei
irkaiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvt
kltandiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqil
pptepllkacrdnlsqwekvirgee

Sequence, based on observed residues (ATOM records):

>d2ouqb_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
shmsictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfel
eklcrfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdl
dhrgfsnstmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgn
rkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegd
emkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsq
wekvirgee

Timeline for d2ouqb_:

• d2ouqb_ first appeared in SCOPe 2.04
  
• d2ouqb_ is called d2ouqb1 in SCOPe 2.06
  
• d2ouqb_ appears in the current release, SCOPe 2.08, called d2ouqb1