SCOPe 2.08: Domain d2oc3a_: 2oc3 A:

Lineage for d2oc3a_ (2oc3 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d2oc3a_: 2oc3 A: [243314]
   automated match to d4ikca_

Details for d2oc3a_

PDB Entry: 2oc3, 1.5 Å

PDB Description: crystal structure of the catalytic domain of human protein tyrosine phosphatase non-receptor type 18

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 18

SCOPe Domain Sequences for d2oc3a_:

Sequence, based on SEQRES records:

>d2oc3a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dsarsflerlearggregavlagefsdiqacsaawkadgvcstvagsrpenvrknrykdv
lpydqtrvilsllqeeghsdyingnfirgvdgslayiatqgplphtlldfwrlvwefgvk
vilmacreiengrkrcerywaqeqeplqtglfcitlikekwlnedimlrtlkvtfqkesr
svyqlqymswpdrgvpsspdhmlamveearrlqgsgpeplcvhcsagcgrtgvlctvdyv
rqllltqmippdfslfdvvlkmrkqrpaavqteeqyrflyhtvaqmfc

Sequence, based on observed residues (ATOM records):

>d2oc3a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dsasflerlavlagefsdiqacsaawkadgvcstvagsrpenvrknrykdvlpydqtrvi
lsllqeeghsdyingnfirgvdgslayiatqgplphtlldfwrlvwefgvkvilmacrei
engrkrcerywaqeqeplqtglfcitlikekwlnedimlrtlkvtfqkesrsvyqlqyms
wpdrgvpsspdhmlamveearrlqgsgpeplcvhcsagcgrtgvlctvdyvrqllltqmi
ppdfslfdvvlkmrkqrpaavqteeqyrflyhtvaqmfc

Timeline for d2oc3a_:

• d2oc3a_ first appeared in SCOPe 2.04
  
• d2oc3a_ appears in SCOPe 2.07