SCOPe 2.04: Domain d2o2cb_: 2o2c B:

Lineage for d2o2cb_ (2o2c B:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.80: SIS domain [53696] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345

4. Superfamily c.80.1: SIS domain [53697] (4 families)

5. Family c.80.1.2: Phosphoglucose isomerase, PGI [53701] (2 proteins)
   permutation of the double-SIS domain fold
   automatically mapped to Pfam PF00342

6. Protein Phosphoglucose isomerase, PGI [53702] (7 species)
   moonlights as neuroleukin, autocrine motility factor, and differentiation mediator

7. Species Trypanosoma brucei [TaxId:5702] [255518] (2 PDB entries)

8. Domain d2o2cb_: 2o2c B: [243284]
   automated match to d1q50a_
   complexed with g6q, gol

Details for d2o2cb_

PDB Entry: 2o2c, 1.58 Å

PDB Description: crystal structure of phosphoglucose isomerase from t. brucei containing glucose-6-phosphate in the active site

PDB Compounds: (B:) Glucose-6-phosphate isomerase, glycosomal

SCOPe Domain Sequences for d2o2cb_:

Sequence; same for both SEQRES and ATOM records:

>d2o2cb_ c.80.1.2 (B:) Phosphoglucose isomerase, PGI {Trypanosoma brucei [TaxId: 5702]}
gadadttltscaswtqlqklyeqygdepikkhfetdsergqrysvkvslgskdenflfld
yskshindeikcallrlaeergirqfvqsvfrgervnttenrpvlhialrnrsnrpiyvd
gkdvmpavnkvldqmrsfsekvrtgewkghtgkairhvvnigiggsdlgpvmatealkpf
sqrdlslhfvsnvdgthiaevlksidieatlfivasktfttqetitnalsarralldylr
srgidekgsvakhfvalstnnqkvkefgideenmfqfwdwvggrysmwsaiglpimisig
yenfvelltgahvidehfanappeqnvplllalvgvwyinffgavthailpydqylwrlp
aylqqldmesngkyvtrsgktvstltgpiifgeagtngqhafyqlihqgtnlipcdfiga
iqsqnkigdhhkifmsnffaqtealmigkspsevrreleaagersaekinallphktfig
grpsntlliksltpralgaiiamyehkvlvqgaiwgidsydqwgvelgkvlaksilpqlr
pgmrvnnhdsstnglinmfnelsh

Timeline for d2o2cb_:

• d2o2cb_ is new in SCOPe 2.04-stable
  
• d2o2cb_ appears in SCOPe 2.05
  
• d2o2cb_ appears in the current release, SCOPe 2.08