SCOPe 2.06: Domain d2noab_: 2noa B:

Lineage for d2noab_ (2noa B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Deoxycytidine kinase [89657] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)

8. Domain d2noab_: 2noa B: [243213]
   automated match to d1p60a_
   complexed with 3tc, adp

Details for d2noab_

PDB Entry: 2noa, 1.8 Å

PDB Description: the structure of deoxycytidine kinase complexed with lamivudine and adp.

PDB Compounds: (B:) Deoxycytidine kinase

SCOPe Domain Sequences for d2noab_:

Sequence, based on SEQRES records:

>d2noab_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesesmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l

Sequence, based on observed residues (ATOM records):

>d2noab_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqggnvlqmmyekperwsf
tfqtyaclsriraqlaslngdaekpvlffersvysdryifasnlyesesmnetewtiyqd
whdwmnnqgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykheswllh
rtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

Timeline for d2noab_:

• d2noab_ first appeared in SCOPe 2.04
  
• d2noab_ appears in SCOPe 2.05
  
• d2noab_ appears in SCOPe 2.07
  
• d2noab_ appears in the current release, SCOPe 2.08