Lineage for d2laga_ (2lag A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991730Protein Interferon-alpha 2a [47314] (1 species)
  7. 1991731Species Human (Homo sapiens) [TaxId:9606] [47315] (9 PDB entries)
  8. 1991745Domain d2laga_: 2lag A: [242823]
    Other proteins in same PDB: d2lagb1, d2lagb2
    automated match to d1itfa_

Details for d2laga_

PDB Entry: 2lag (more details)

PDB Description: Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY
PDB Compounds: (A:) Interferon alpha-2

SCOPe Domain Sequences for d2laga_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2laga_ a.26.1.3 (A:) Interferon-alpha 2a {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2laga_:

Click to download the PDB-style file with coordinates for d2laga_.
(The format of our PDB-style files is described here.)

Timeline for d2laga_: