SCOPe 2.08: Domain d2i19b_: 2i19 B:

Lineage for d2i19b_ (2i19 B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (46 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [230726] (37 PDB entries)

8. Domain d2i19b_: 2i19 B: [242083]
   automated match to d2ewga_
   complexed with 1by, mg

Details for d2i19b_

PDB Entry: 2i19, 2.28 Å

PDB Description: T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate

PDB Compounds: (B:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d2i19b_:

Sequence, based on SEQRES records:

>d2i19b_ a.128.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llslspnnngeeddgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyr
hpdvtvqcaindglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmf
dsnkldpdvsqptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvt
eelamlmgeyfqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefka
nygsgdsekvatvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwg
ktykrqk

Sequence, based on observed residues (ATOM records):

>d2i19b_ a.128.1.0 (B:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llslseddgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyrhpdvtv
qcaindglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmfdsnkld
pdvsqptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvteelaml
mgeyfqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefkanygsgd
sekvatvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwgktykrq
k

Timeline for d2i19b_:

• d2i19b_ first appeared in SCOPe 2.04
  
• d2i19b_ appears in SCOPe 2.07