SCOPe 2.08: Domain d2hnia1: 2hni A:1-188

Lineage for d2hnia1 (2hni A:1-188)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.104: Class II aaRS and biotin synthetases [55680] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.104.1: Class II aaRS and biotin synthetases [55681] (5 families)

5. Family d.104.1.2: Biotin holoenzyme synthetase [55707] (3 proteins)

6. Protein Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain [143640] (1 species)

7. Species Pyrococcus horikoshii [TaxId:53953] [143641] (27 PDB entries)
   Uniprot O57883 1-188

8. Domain d2hnia1: 2hni A:1-188 [242046]
   Other proteins in same PDB: d2hnia2, d2hnib2
   automated match to d2djza1
   complexed with acy; mutant

Details for d2hnia1

PDB Entry: 2hni, 1.9 Å

PDB Description: crystal structure of biotin protein ligase from pyrococcus horikoshii ot3, k111a mutation

PDB Compounds: (A:) 235aa long hypothetical biotin-[acetyl-CoA-carboxylase] ligase

SCOPe Domain Sequences for d2hnia1:

Sequence, based on SEQRES records:

>d2hnia1 d.104.1.2 (A:1-188) Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain {Pyrococcus horikoshii [TaxId: 53953]}
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgrlnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmil

Sequence, based on observed residues (ATOM records):

>d2hnia1 d.104.1.2 (A:1-188) Biotin--[acetyl-CoA-carboxylase] ligase catalytic domain {Pyrococcus horikoshii [TaxId: 53953]}
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgrespegglwlsiv
lspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegkgdkiv
lgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdilnlvrdn
mil

Timeline for d2hnia1:

• d2hnia1 first appeared in SCOPe 2.04
  
• d2hnia1 appears in SCOPe 2.07