Lineage for d2g19a_ (2g19 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2070014Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2070786Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2071201Family b.82.2.15: proly-4-hydroxylase (P4H, PHD) like [254173] (3 protein domains)
    Pfam PF13640; PubMed 16782814
  6. 2071202Protein HIF-P4H2, PHD2 [254392] (1 species)
  7. 2071203Species Human (Homo sapiens) [TaxId:9606] [254828] (1 PDB entry)
  8. 2071204Domain d2g19a_: 2g19 A: [241900]
    complexed with 4hg, fe2

Details for d2g19a_

PDB Entry: 2g19 (more details), 1.7 Å

PDB Description: Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)
PDB Compounds: (A:) Egl nine homolog 1

SCOPe Domain Sequences for d2g19a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2g19a_ b.82.2.15 (A:) HIF-P4H2, PHD2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2g19a_:

Click to download the PDB-style file with coordinates for d2g19a_.
(The format of our PDB-style files is described here.)

Timeline for d2g19a_: