Lineage for d2ewyc_ (2ewy C:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2061036Family b.50.1.0: automated matches [191552] (1 protein)
    not a true family
  6. 2061037Protein automated matches [190954] (10 species)
    not a true protein
  7. 2061062Species Human (Homo sapiens) [TaxId:9606] [193159] (12 PDB entries)
  8. 2061083Domain d2ewyc_: 2ewy C: [241801]
    automated match to d3zkqa_
    complexed with dbo

Details for d2ewyc_

PDB Entry: 2ewy (more details), 3.1 Å

PDB Description: Crystal structure of human BACE2 in complex with a hydroxyethylenamine transition-state inhibitor
PDB Compounds: (C:) Beta-secretase 2

SCOPe Domain Sequences for d2ewyc_:

Sequence, based on SEQRES records: (download)

>d2ewyc_ b.50.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggieps
lykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfd
avveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilp
qlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeia
gaavseisgpfstedvasncvpa

Sequence, based on observed residues (ATOM records): (download)

>d2ewyc_ b.50.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdtersst
yrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngil
glayatlakpsssletffdslvtqanipnvfsmqmcganggslvlggiepslykgdiwyt
pikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveavara
slipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilpqlyiqpmmg
aglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisg
pfstedvasncvpa

SCOPe Domain Coordinates for d2ewyc_:

Click to download the PDB-style file with coordinates for d2ewyc_.
(The format of our PDB-style files is described here.)

Timeline for d2ewyc_: