SCOPe 2.07: Domain d2cn5a1: 2cn5 A:210-504

Lineage for d2cn5a1 (2cn5 A:210-504)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d2cn5a1: 2cn5 A:210-504 [241467]
   Other proteins in same PDB: d2cn5a2
   automated match to d2ycfa_
   complexed with adp, cl, mg, no3

Details for d2cn5a1

PDB Entry: 2cn5, 2.25 Å

PDB Description: crystal structure of human chk2 in complex with adp

PDB Compounds: (A:) serine/threonine-protein kinase chk2

SCOPe Domain Sequences for d2cn5a1:

Sequence, based on SEQRES records:

>d2cn5a1 d.144.1.0 (A:210-504) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsareadpaln
veteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfy
qmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtpt
ylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfip
evwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllseene

Sequence, based on observed residues (ATOM records):

>d2cn5a1 d.144.1.0 (A:210-504) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrnveteieilkklnhp
ciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengi
ihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtag
ynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlv
kkllvvdpkarftteealrhpwlqdedmkrkfqdllseene

Timeline for d2cn5a1:

• d2cn5a1 first appeared in SCOPe 2.04, called d2cn5a_
  
• d2cn5a1 appears in SCOPe 2.06
  
• d2cn5a1 appears in the current release, SCOPe 2.08