SCOPe 2.08: Domain d2c6qg1: 2c6q G:10-337

Lineage for d2c6qg1 (2c6q G:10-337)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (16 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [230557] (5 PDB entries)

8. Domain d2c6qg1: 2c6q G:10-337 [241423]
   Other proteins in same PDB: d2c6qa2, d2c6qb2, d2c6qc2, d2c6qd2, d2c6qe2, d2c6qf2, d2c6qg2, d2c6qh2
   automated match to d2bznb_
   complexed with imp, ndp

Details for d2c6qg1

PDB Entry: 2c6q, 1.7 Å

PDB Description: crystal structure of human guanosine monophosphate reductase 2 gmpr2 in complex with imp and nadph

PDB Compounds: (G:) GMP reductase 2

SCOPe Domain Sequences for d2c6qg1:

Sequence, based on SEQRES records:

>d2c6qg1 c.1.5.0 (G:10-337) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlck
fslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicld
vangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttr
kktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghs
esggelierdgkkyklfygmssemamkkyaggvaeyrasegktvevpfkgdvehtirdil
ggirstctyvgaaklkelsrrttfirvt

Sequence, based on observed residues (ATOM records):

>d2c6qg1 c.1.5.0 (G:10-337) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ldfkdvllrpkrstlksrsevdltrsfsfrnskqtysgvpiiaanmdtvgtfemakvlck
fslftavhkhyslvqwqefagqnpdclehlaassgtgssdfeqleqileaipqvkyicld
vangysehfvefvkdvrkrfpqhtimagnvvtgemveelilsgadiikvgigpgsvcttr
kktgvgypqlsavmecadaahglkghiisdggcscpgdvakafgagadfvmlggmlaghs
esggelierdgkkyklfygmssemamkkyasegktvevpfkgdvehtirdilggirstct
yvgaaklkelsrrttfirvt

Timeline for d2c6qg1:

• d2c6qg1 first appeared in SCOPe 2.04, called d2c6qg_
  
• d2c6qg1 appears in SCOPe 2.07