SCOPe 2.07: Domain d2b3oa3: 2b3o A:216-526

Lineage for d2b3oa3 (2b3o A:216-526)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d2b3oa3: 2b3o A:216-526 [241258]
   Other proteins in same PDB: d2b3oa1, d2b3oa2
   automated match to d2shpa1

Details for d2b3oa3

PDB Entry: 2b3o, 2.8 Å

PDB Description: Crystal structure of human tyrosine phosphatase SHP-1

PDB Compounds: (A:) Tyrosine-protein phosphatase, non-receptor type 6

SCOPe Domain Sequences for d2b3oa3:

Sequence, based on SEQRES records:

>d2b3oa3 c.45.1.0 (A:216-526) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trvnaadienrvlelnkkqesedtakagfweefeslqkqevknlhqrlegqrpenkgknr
yknilpfdhsrvilqgrdsnipgsdyinanyiknqllgpdenaktyiasqgcleatvndf
wqmawqensrvivmttrevekgrnkcvpywpevgmqraygpysvtncgehdtteyklrtl
qvspldngdlireiwhyqylswpdhgvpsepggvlsfldqinqrqeslphagpiivhcsa
gigrtgtiividmlmenistkgldcdidiqktiqmvraqrsgmvqteaqykfiyvaiaqf
iettkkklevl

Sequence, based on observed residues (ATOM records):

>d2b3oa3 c.45.1.0 (A:216-526) automated matches {Human (Homo sapiens) [TaxId: 9606]}
trvnaadienrfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgr
dsnipgsdyinanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttr
evekgrnkcvpywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhy
qylswpdhgvpsepggvlsfldqinqrqeslphagpiivhcsagigrtgtiividmlmen
istkgldcdidiqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkklevl

Timeline for d2b3oa3:

• d2b3oa3 first appeared in SCOPe 2.04
  
• d2b3oa3 appears in SCOPe 2.06
  
• d2b3oa3 appears in the current release, SCOPe 2.08