SCOPe 2.08: Domain d2a2zc_: 2a2z C:

Lineage for d2a2zc_ (2a2z C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Deoxycytidine kinase [89657] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)

8. Domain d2a2zc_: 2a2z C: [241197]
   automated match to d1p60a_
   complexed with ca, dcz, mg, udp
   has additional insertions and/or extensions that are not grouped together

Details for d2a2zc_

PDB Entry: 2a2z, 3.02 Å

PDB Description: Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate

PDB Compounds: (C:) Deoxycytidine kinase

SCOPe Domain Sequences for d2a2zc_:

Sequence, based on SEQRES records:

>d2a2zc_ c.37.1.1 (C:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnvlqmmyekperwsf
tfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnetewti
yqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykhes
wllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

Sequence, based on observed residues (ATOM records):

>d2a2zc_ c.37.1.1 (C:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnvlqmmyekperwsf
tfqtyaclsriraqlaslngkekpvlffersvysdryifasnlyesecmnetewtiyqdw
hdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykheswllh
rtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

Timeline for d2a2zc_:

• d2a2zc_ first appeared in SCOPe 2.04
  
• d2a2zc_ appears in SCOPe 2.07