SCOPe 2.05: Domain d3uwoa_: 3uwo A:

Lineage for d3uwoa_ (3uwo A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.0: automated matches [191323] (1 protein)
   not a true family

6. Protein automated matches [190123] (96 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:208964] [226294] (10 PDB entries)

8. Domain d3uwoa_: 3uwo A: [239879]
   automated match to d3uwob_
   complexed with 0dj

Details for d3uwoa_

PDB Entry: 3uwo, 1.7 Å

PDB Description: Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation

PDB Compounds: (A:) thymidylate kinase

SCOPe Domain Sequences for d3uwoa_:

Sequence, based on SEQRES records:

>d3uwoa_ c.37.1.0 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
glfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllapsdepma
adtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpeariaalesf
vqgdlrpdltlvfdlpveiglaraaargrldrfeqedrrffeavrqtylqraaqaperyq
vldaglplaevqagldrllpnller

Sequence, based on observed residues (ATOM records):

>d3uwoa_ c.37.1.0 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
glfvtlegpegagkstnrdylaerlrergievqltrepggtplaerirelllapsdepma
adtelllmfaaraqhlagvirpalargavvlcdrftdatyayqgggrglpeariaalesf
vqgdlrpdltlvfdlpvrldrfeqedrrffeavrqtylqraaqaperyqvldaglplaev
qagldrllpnller

Timeline for d3uwoa_:

• d3uwoa_ first appeared in SCOPe 2.04
  
• d3uwoa_ appears in SCOPe 2.06
  
• d3uwoa_ appears in the current release, SCOPe 2.08