SCOPe 2.08: Domain d3e37a_: 3e37 A:

Lineage for d3e37a_ (3e37 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (13 PDB entries)
   Uniprot P49354

8. Domain d3e37a_: 3e37 A: [239238]
   Other proteins in same PDB: d3e37b_
   automated match to d1d8da_
   complexed with ed5, zn

Details for d3e37a_

PDB Entry: 3e37, 1.8 Å

PDB Description: protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

SCOPe Domain Sequences for d3e37a_:

Sequence; same for both SEQRES and ATOM records:

>d3e37a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d3e37a_:

• d3e37a_ first appeared in SCOPe 2.04
  
• d3e37a_ appears in SCOPe 2.07