SCOPe 2.04: Domain d2tnfa_: 2tnf A:

Lineage for d2tnfa_ (2tnf A:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.22: TNF-like [49841] (1 superfamily)
   sandwich, 10 strands in 2 sheets; jelly-roll

4. Superfamily b.22.1: TNF-like [49842] (2 families)

5. Family b.22.1.1: TNF-like [49843] (15 proteins)

6. Protein Tumor necrosis factor (TNF) [49848] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

8. Domain d2tnfa_: 2tnf A: [23880]
   complexed with ipa, trs

Details for d2tnfa_

PDB Entry: 2tnf, 1.4 Å

PDB Description: 1.4 a resolution structure of mouse tumor necrosis factor, towards modulation of its selectivity and trimerisation

PDB Compounds: (A:) protein (tumor necrosis factor alpha)

SCOPe Domain Sequences for d2tnfa_:

Sequence; same for both SEQRES and ATOM records:

>d2tnfa_ b.22.1.1 (A:) Tumor necrosis factor (TNF) {Mouse (Mus musculus) [TaxId: 10090]}
sdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvysqvlfkgqg
cpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylggvfqlekg
dqlsaevnlpkyldfaesgqvyfgvial

Timeline for d2tnfa_:

• d2tnfa_ first appeared (with stable ids) in SCOP 1.55
  
• d2tnfa_ appears in SCOPe 2.03
  
• d2tnfa_ appears in SCOPe 2.05
  
• d2tnfa_ appears in the current release, SCOPe 2.08