SCOP 1.69: Domain d1tnfc_: 1tnf C:

Lineage for d1tnfc_ (1tnf C:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.22: TNF-like [49841] (1 superfamily)
   sandwich, 10 strands in 2 sheets; jelly-roll

4. Superfamily b.22.1: TNF-like [49842] (1 family)

5. Family b.22.1.1: TNF-like [49843] (11 proteins)

6. Protein Tumor necrosis factor (TNF) [49848] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49849] (6 PDB entries)

8. Domain d1tnfc_: 1tnf C: [23873]

Details for d1tnfc_

PDB Entry: 1tnf, 2.6 Å

PDB Description: the structure of tumor necrosis factor-alpha at 2.6 angstroms resolution. implications for receptor binding

SCOP Domain Sequences for d1tnfc_:

Sequence, based on SEQRES records:

>d1tnfc_ b.22.1.1 (C:) Tumor necrosis factor (TNF) {Human (Homo sapiens)}
rtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfk
gqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfq
lekgdrlsaeinrpdyldfaesgqvyfgiial

Sequence, based on observed residues (ATOM records):

>d1tnfc_ b.22.1.1 (C:) Tumor necrosis factor (TNF) {Human (Homo sapiens)}
rtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfk
gqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfq
lekgdrlsaeinrpdyllfaesgqvyfgiial

Timeline for d1tnfc_:

• d1tnfc_ first appeared (with stable ids) in SCOP 1.55
  
• d1tnfc_ appears in SCOP 1.67
  
• d1tnfc_ appears in SCOP 1.71
  
• d1tnfc_ appears in the current release, SCOPe 2.08