SCOPe 2.07: Domain d1shzf_: 1shz F:

Lineage for d1shzf_ (1shz F:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.91: Regulator of G-protein signaling, RGS [48096] (1 superfamily)
   multihelical; consists of two all-alpha subdomains
   contains a 4-helical bundle with left-handed twist and up-and-down topology

4. Superfamily a.91.1: Regulator of G-protein signaling, RGS [48097] (2 families)

5. Family a.91.1.0: automated matches [191379] (1 protein)
   not a true family

6. Protein automated matches [190464] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187381] (38 PDB entries)

8. Domain d1shzf_: 1shz F: [238533]
   Other proteins in same PDB: d1shza1, d1shza2, d1shzd1, d1shzd2
   automated match to d3cx8b_
   complexed with alf, gdp, mg

Details for d1shzf_

PDB Entry: 1shz, 2.85 Å

PDB Description: crystal structure of the p115rhogef rgrgs domain in a complex with galpha(13):galpha(i1) chimera

PDB Compounds: (F:) Rho guanine nucleotide exchange factor 1

SCOPe Domain Sequences for d1shzf_:

Sequence, based on SEQRES records:

>d1shzf_ a.91.1.0 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
glvpvsiigaededfeneletnseeqnsqfqsleqvkrrpahlmallqhvalqfepgpll
cclhadmlgslgpkeakkafldfyhsflektavlrvpvppnvafeldrtradlisedvqr
rfvqevvqsqqvavgrqledfrskrlmgmtpweqelaqleawvgrdrasyearerhvaer
llmhleemqhtistdeeksaavvnaiglymrhlgvrt

Sequence, based on observed residues (ATOM records):

>d1shzf_ a.91.1.0 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
glvpvsiigaededfenesqfqsleqvkrrpahlmallqhvalqfepgpllcclhadmlg
pkeakkafldfyhsflektavlrvpvppnvafelvqrrfvqevvqsqqvavgrqledfrs
krlmgmtpweqelaqleawsyearerhvaerllmhleemqhtistdeeksaavvnaigly
mrhlgvrt

Timeline for d1shzf_:

• d1shzf_ first appeared in SCOPe 2.04
  
• d1shzf_ appears in SCOPe 2.06
  
• d1shzf_ appears in the current release, SCOPe 2.08