SCOPe 2.07: Domain d4kwpa_: 4kwp A:

Lineage for d4kwpa_ (4kwp A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (180 PDB entries)

8. Domain d4kwpa_: 4kwp A: [238425]
   automated match to d3q9za_
   complexed with dms, edo, exx, peg, pge, so4

Details for d4kwpa_

PDB Entry: 4kwp, 1.25 Å

PDB Description: Crystal Structure of Human CK2-alpha in complex with a benzimidazole inhibitor (K164) at 1.25 A resolution

PDB Compounds: (A:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d4kwpa_:

Sequence; same for both SEQRES and ATOM records:

>d4kwpa_ d.144.1.7 (A:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkd

Timeline for d4kwpa_:

• d4kwpa_ first appeared in SCOPe 2.03
  
• d4kwpa_ appears in SCOPe 2.06
  
• d4kwpa_ appears in the current release, SCOPe 2.08