SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d4k1qa_ (4k1q A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2067964Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  4. 2067965Superfamily b.74.1: Carbonic anhydrase [51069] (2 families) (S)
  5. 2067966Family b.74.1.1: Carbonic anhydrase [51070] (2 protein domains)
    automatically mapped to Pfam PF00194
  6. 2067967Protein Carbonic anhydrase [51071] (10 species)
  7. 2068005Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (613 PDB entries)
    Uniprot P00918
  8. 2068392Domain d4k1qa_: 4k1q A: [238382]
    automated match to d1ugda_
    complexed with zn; mutant

Details for d4k1qa_

PDB Entry: 4k1q (more details), 1.7 Å

PDB Description: Structure of hCAIX mimic (hCAII with 5 mutations in active site)
PDB Compounds: (A:) Carbonic anhydrase 2

SCOPe Domain Sequences for d4k1qa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4k1qa_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghsfqvtfddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdlgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdprg
llpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplknrqikasfk

SCOPe Domain Coordinates for d4k1qa_:

Click to download the PDB-style file with coordinates for d4k1qa_.
(The format of our PDB-style files is described here.)

Timeline for d4k1qa_: