SCOPe 2.08: Domain d4k10a_: 4k10 A:

Lineage for d4k10a_ (4k10 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (46 species)
   not a true protein

7. Species Leishmania major [TaxId:5664] [236738] (6 PDB entries)

8. Domain d4k10a_: 4k10 A: [238157]
   automated match to d4jzba_
   complexed with act, mes, mg, na, ni9, peg

Details for d4k10a_

PDB Entry: 4k10, 2.3 Å

PDB Description: crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and mg2+

PDB Compounds: (A:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d4k10a_:

Sequence, based on SEQRES records:

>d4k10a_ a.128.1.0 (A:) automated matches {Leishmania major [TaxId: 5664]}
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppeklgkigtdiedakcswlavtflttapaekvaefkanygst
dpaavavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykr
q

Sequence, based on observed residues (ATOM records):

>d4k10a_ a.128.1.0 (A:) automated matches {Leishmania major [TaxId: 5664]}
mahmerfqkvyeevqefllgdaekrfemdvhrkgylksmmdttclggkynrglcvvdvae
amakdtqmdaaamervlhdacvcgwmiemlqahflveddimdhsktrrgkpcwylhpgvt
aqvaindglillawatqmalhyfadrpflaevlrvfhdvdltttigqlydvtsmvdsakl
dakvahanttdyveytpfnhrrivvyktayytywlplvmgllvsgtlekvdkkathkvam
vmgeyfqvqddvmdcftppekigtdiedakcswlavtflttapaekvaefkanygstdpa
avavikqlyteqnllarfeeyekavvaeveqliaaleaqnaafaasvkvlwsktykrq

Timeline for d4k10a_:

• d4k10a_ first appeared in SCOPe 2.03
  
• d4k10a_ appears in SCOPe 2.07