SCOPe 2.08: Domain d4m5xb_: 4m5x B:

Lineage for d4m5xb_ (4m5x B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

6. Protein Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82569] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82570] (25 PDB entries)

8. Domain d4m5xb_: 4m5x B: [237645]
   automated match to d1nb8b_
   complexed with br

Details for d4m5xb_

PDB Entry: 4m5x, 2.19 Å

PDB Description: crystal structure of the usp7/hausp catalytic domain

PDB Compounds: (B:) Ubiquitin carboxyl-terminal hydrolase 7

SCOPe Domain Sequences for d4m5xb_:

Sequence, based on SEQRES records:

>d4m5xb_ d.3.1.9 (B:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
kkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyel
qhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrgk
mvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglq
eaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpan
yilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddlsv
rhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

Sequence, based on observed residues (ATOM records):

>d4m5xb_ d.3.1.9 (B:) Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) {Human (Homo sapiens) [TaxId: 9606]}
kkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyel
qhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrgk
mvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglq
eaekgvkfltlppvlhlqlmrfmyddqnikindrfefpeqlpldeflqktdpkdpanyil
havlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghhctnaymlv
yiresklsevlqavtdhdipqqlverlqeekrieaqk

Timeline for d4m5xb_:

• d4m5xb_ first appeared in SCOPe 2.03
  
• d4m5xb_ appears in SCOPe 2.07