SCOPe 2.04: Domain d4ovla_: 4ovl A:

Lineage for d4ovla_ (4ovl A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)

6. Protein Retroviral integrase, catalytic domain [53108] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (42 PDB entries)

8. Domain d4ovla_: 4ovl A: [237439]
   automated match to d4ah9a_
   complexed with 1td, acy, edo, gol, so4

Details for d4ovla_

PDB Entry: 4ovl, 1.7 Å

PDB Description: Interrogating HIV integrase for compounds that bind- a SAMPL challenge

PDB Compounds: (A:) integrase

SCOPe Domain Sequences for d4ovla_:

Sequence, based on SEQRES records:

>d4ovla_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records):

>d4ovla_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkgysagerivdiiatdiq

Timeline for d4ovla_:

• d4ovla_ first appeared in SCOPe 2.03
  
• d4ovla_ appears in SCOPe 2.05
  
• d4ovla_ appears in the current release, SCOPe 2.08