Lineage for d4oksa1 (4oks A:184-325)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1362078Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 1362079Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families) (S)
    division into families based on beta-sheet topologies
  5. 1365362Family c.37.1.14: RNA helicase [52724] (4 proteins)
    duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension
  6. 1365373Protein HCV helicase domain [52725] (1 species)
  7. 1365374Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [52726] (16 PDB entries)
  8. 1365397Domain d4oksa1: 4oks A:184-325 [237408]
    automated match to d1cu1a2
    complexed with 2t9, ca

Details for d4oksa1

PDB Entry: 4oks (more details), 2.25 Å

PDB Description: Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 19 [[6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid]
PDB Compounds: (A:) Serine protease NS3

SCOPe Domain Sequences for d4oksa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4oksa1 c.37.1.14 (A:184-325) HCV helicase domain {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}
ftdnssppavpqsfqvahlhaptgsgkstkvpaayaaqgykvlvlnpsvaatlgfgayms
kahgvdpnirtgvrtittgspitystygkfladggcsggaydiiicdechstdatsilgi
gtvldqaetagarlvvlatatp

SCOPe Domain Coordinates for d4oksa1:

Click to download the PDB-style file with coordinates for d4oksa1.
(The format of our PDB-style files is described here.)

Timeline for d4oksa1: