SCOPe 2.06: Domain d4kvgc_: 4kvg C:

Lineage for d4kvgc_ (4kvg C:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (29 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (179 PDB entries)

8. Domain d4kvgc_: 4kvg C: [237283]
   Other proteins in same PDB: d4kvga2
   automated match to d1c1ya_
   complexed with edo, gtp, mg

Details for d4kvgc_

PDB Entry: 4kvg, 1.65 Å

PDB Description: Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1

PDB Compounds: (C:) ras-related protein rap-1a

SCOPe Domain Sequences for d4kvgc_:

Sequence, based on SEQRES records:

>d4kvgc_ c.37.1.8 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mreyklvvlgsvgvgksaltvqfvqgifvekydptiedsyrkqvevdcqqcmleildtag
teeftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtedvpmilvgnkcdl
edervvgkeqgqnlarqwcncaflessakskinvneifydlvrqin

Sequence, based on observed residues (ATOM records):

>d4kvgc_ c.37.1.8 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mreyklvvlgsvgvgksaltvqfvqgifvekydptiedsyrkqvevdcqqcmleildtag
trdlymkngqgfalvysitaqstfndlqdlreqilrvkdtedvpmilvgnkcdledervv
gkeqgqnlarqwcncaflessakskinvneifydlvrqin

Timeline for d4kvgc_:

• d4kvgc_ first appeared in SCOPe 2.03
  
• d4kvgc_ appears in SCOPe 2.05
  
• d4kvgc_ appears in SCOPe 2.07
  
• d4kvgc_ appears in the current release, SCOPe 2.08