SCOPe 2.07: Domain d4jgda_: 4jgd A:

Lineage for d4jgda_ (4jgd A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein Dihydroorotate dehydrogenase [51397] (8 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51400] (68 PDB entries)

8. Domain d4jgda_: 4jgd A: [237258]
   automated match to d3kvja_
   complexed with 4jg, det, fmn, oro, so4

Details for d4jgda_

PDB Entry: 4jgd, 2.05 Å

PDB Description: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016

PDB Compounds: (A:) Dihydroorotate dehydrogenase (quinone), mitochondrial

SCOPe Domain Sequences for d4jgda_:

Sequence; same for both SEQRES and ATOM records:

>d4jgda_ c.1.4.1 (A:) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
dhrr

Timeline for d4jgda_:

• d4jgda_ first appeared in SCOPe 2.03
  
• d4jgda_ appears in SCOPe 2.06
  
• d4jgda_ appears in the current release, SCOPe 2.08