Lineage for d4ciaa_ (4cia A:)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1382311Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 1382312Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9
  5. 1382828Family c.69.1.5: Serine carboxypeptidase-like [53499] (4 proteins)
    automatically mapped to Pfam PF00450
  6. 1382829Protein Human 'protective protein', HPP [53504] (1 species)
    synonyms: cathepsin A, carboxypeptidase L
  7. 1382830Species Human (Homo sapiens) [TaxId:9606] [53505] (4 PDB entries)
  8. 1382833Domain d4ciaa_: 4cia A: [237118]
    automated match to d1ivya_
    complexed with 6kz, cd, nag

Details for d4ciaa_

PDB Entry: 4cia (more details), 1.98 Å

PDB Description: crystal structure of cathepsin a, complexed with compound 1
PDB Compounds: (A:) lysosomal protective protein

SCOPe Domain Sequences for d4ciaa_:

Sequence, based on SEQRES records: (download)

>d4ciaa_ c.69.1.5 (A:) Human 'protective protein', HPP {Human (Homo sapiens) [TaxId: 9606]}
rapdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpg
cssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndt
evaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgng
lssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevariv
gnsglniynlyapcaggvpshfryekdtvvvqdlgniftrlplkrmwhqallrsgdkvrm
dppctnttaastylnnpyvrkalnipeqlpqwdmcnflvnlqyrrlyrsmnsqylkllss
qkyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwlvkygdsgeqiagfvkefshi
afltikgaghmvptdkplaaftmfsrflnkqpye

Sequence, based on observed residues (ATOM records): (download)

>d4ciaa_ c.69.1.5 (A:) Human 'protective protein', HPP {Human (Homo sapiens) [TaxId: 9606]}
rapdqdeiqrlpglakqpsfrqysgylkgsgskhlhywfvesqkdpenspvvlwlnggpg
cssldglltehgpflvqpdgvtleynpyswnlianvlylespagvgfsysddkfyatndt
evaqsnfealqdffrlfpeyknnklfltgesyagiyiptlavlvmqdpsmnlqglavgng
lssyeqndnslvyfayyhgllgnrlwsslqthccsqnkcnfydnkdlecvtnlqevariv
gnsglniynlyapcaggvpmdppctnttaastylnnpyvrkalnipeqlpqwdmcnflvn
lqyrrlyrsmnsqylkllssqkyqillyngdvdmacnfmgdewfvdslnqkmevqrrpwl
vkygsgeqiagfvkefshiafltikgaghmvptdkplaaftmfsrflnkqpye

SCOPe Domain Coordinates for d4ciaa_:

Click to download the PDB-style file with coordinates for d4ciaa_.
(The format of our PDB-style files is described here.)

Timeline for d4ciaa_: