Lineage for d3weha_ (3weh A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2010547Fold a.128: Terpenoid synthases [48575] (1 superfamily)
    multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers
  4. 2010548Superfamily a.128.1: Terpenoid synthases [48576] (6 families) (S)
    duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J
  5. 2010672Family a.128.1.2: Squalene synthase [48580] (2 protein domains)
    automatically mapped to Pfam PF00494
  6. 2010678Protein automated matches [191305] (1 species)
    not a true protein
  7. 2010679Species Human (Homo sapiens) [TaxId:9606] [190011] (24 PDB entries)
  8. 2010699Domain d3weha_: 3weh A: [236951]
    automated match to d3vj8a_
    complexed with mg, ps7

Details for d3weha_

PDB Entry: 3weh (more details), 1.87 Å

PDB Description: Crystal structure of the human squalene synthase in complex with presqualene pyrophosphate
PDB Compounds: (A:) Squalene synthase

SCOPe Domain Sequences for d3weha_:

Sequence, based on SEQRES records: (download)

>d3weha_ a.128.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmtisvekkv
pllhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigm
aefldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqkt
niirdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvi
tylsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmdatnmpav
kaiiyqymeeiyhripdsdpsssktrqiistirtq

Sequence, based on observed residues (ATOM records): (download)

>d3weha_ a.128.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmtisvekkv
pllhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigm
aefldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqkt
niirdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvi
tylsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkiqavtlmmdatnmpavkai
iyqymeeiyhripdsdpsssktrqiistirtq

SCOPe Domain Coordinates for d3weha_:

Click to download the PDB-style file with coordinates for d3weha_.
(The format of our PDB-style files is described here.)

Timeline for d3weha_: