SCOPe 2.08: Domain d3wefb_: 3wef B:

Lineage for d3wefb_ (3wef B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.2: Squalene synthase [48580] (2 proteins)
   automatically mapped to Pfam PF00494

6. Protein automated matches [191305] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [190011] (24 PDB entries)

8. Domain d3wefb_: 3wef B: [236945]
   automated match to d3vj8a_
   complexed with fps

Details for d3wefb_

PDB Entry: 3wef, 2.35 Å

PDB Description: crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate

PDB Compounds: (B:) Squalene synthase

SCOPe Domain Sequences for d3wefb_:

Sequence; same for both SEQRES and ATOM records:

>d3wefb_ a.128.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ssslktcykylnqtsrsfaaviqaldgemrnavcifylvlraldtleddmtisvekkvpl
lhnfhsflyqpdwrfmeskekdrqvledfptislefrnlaekyqtviadicrrmgigmae
fldkhvtseqewdkychyvaglvgiglsrlfsasefedplvgedteransmglflqktni
irdyledqqggrefwpqevwsryvkklgdfakpenidlavqclnelitnalhhipdvity
lsrlrnqsvfnfcaipqvmaiatlaacynnqqvfkgavkirkgqavtlmmdatnmpavka
iiyqymeeiyhripdsdpsssktrqiistirtq

Timeline for d3wefb_:

• d3wefb_ first appeared in SCOPe 2.03
  
• d3wefb_ appears in SCOPe 2.07