Lineage for d4ll5a_ (4ll5 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220589Protein Proto-oncogene serine/threonine-protein kinase Pim-1 [118133] (1 species)
    OPK group(?); PIM subfamily; serine/threonine kinase
  7. 2220590Species Human (Homo sapiens) [TaxId:9606] [118134] (99 PDB entries)
    Uniprot P11309 33-305 ! Uniprot P11309 32-308
  8. 2220614Domain d4ll5a_: 4ll5 A: [236779]
    automated match to d3uixa_
    complexed with ca, gol, sk8

Details for d4ll5a_

PDB Entry: 4ll5 (more details), 2 Å

PDB Description: crystal structure of pim-1 in complex with the fluorescent compound skf86002
PDB Compounds: (A:) Serine/threonine-protein kinase pim-1

SCOPe Domain Sequences for d4ll5a_:

Sequence, based on SEQRES records: (download)

>d4ll5a_ d.144.1.7 (A:) Proto-oncogene serine/threonine-protein kinase Pim-1 {Human (Homo sapiens) [TaxId: 9606]}
lesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvll
kkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvle
avrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewi
ryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwclal
rpsdrptfeeiqnhpwmqdvllpqetaeihlh

Sequence, based on observed residues (ATOM records): (download)

>d4ll5a_ d.144.1.7 (A:) Proto-oncogene serine/threonine-protein kinase Pim-1 {Human (Homo sapiens) [TaxId: 9606]}
lesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgetrvpmevvllkkvs
sgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvleavrh
chncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewiryhr
yhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwclalrpsd
rptfeeiqnhpwmqdvllpqetaeihlh

SCOPe Domain Coordinates for d4ll5a_:

Click to download the PDB-style file with coordinates for d4ll5a_.
(The format of our PDB-style files is described here.)

Timeline for d4ll5a_: