Lineage for d3w2ce_ (3w2c E:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218253Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
    OPK group; AIRK subfamily; serine/threonine kinase
  7. 2218254Species Human (Homo sapiens) [TaxId:9606] [90039] (62 PDB entries)
  8. 2218319Domain d3w2ce_: 3w2c E: [236654]
    automated match to d1ol5a_
    complexed with n15

Details for d3w2ce_

PDB Entry: 3w2c (more details), 2.45 Å

PDB Description: Structure of Aurora kinase A complexed to benzoimidazole-indazole inhibitor XV
PDB Compounds: (E:) Aurora kinase A

SCOPe Domain Sequences for d3w2ce_:

Sequence, based on SEQRES records: (download)

>d3w2ce_ d.144.1.7 (E:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrmhd
ekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhn
psqrpmlrevlehpwitanss

Sequence, based on observed residues (ATOM records): (download)

>d3w2ce_ d.144.1.7 (E:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqeveiqshlrhpnilrlygy
fhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyckpenlllgsage
lkiadtldylppemievdlwslgvlcyeflvgkppfeantyqykrisrveftfpdfvteg
ardlisrllkhnphpwitanss

SCOPe Domain Coordinates for d3w2ce_:

Click to download the PDB-style file with coordinates for d3w2ce_.
(The format of our PDB-style files is described here.)

Timeline for d3w2ce_: