Lineage for d3w10a_ (3w10 A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2979788Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
    OPK group; AIRK subfamily; serine/threonine kinase
  7. 2979789Species Human (Homo sapiens) [TaxId:9606] [90039] (72 PDB entries)
  8. 2979866Domain d3w10a_: 3w10 A: [236652]
    automated match to d3dfcb_
    complexed with ro9

Details for d3w10a_

PDB Entry: 3w10 (more details), 2.7 Å

PDB Description: Aurora kinase A complexed to pyrazole aminoquinoline I
PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d3w10a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3w10a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhapssrraalcgtldylppemiegrm
hdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllk
hnpsqrpmlrevlehpwitanss

SCOPe Domain Coordinates for d3w10a_:

Click to download the PDB-style file with coordinates for d3w10a_.
(The format of our PDB-style files is described here.)

Timeline for d3w10a_: