Lineage for d4ccba_ (4ccb A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2546221Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2546222Protein automated matches [190417] (29 species)
    not a true protein
  7. 2546365Species Human (Homo sapiens) [TaxId:9606] [187294] (1145 PDB entries)
  8. 2546758Domain d4ccba_: 4ccb A: [236321]
    automated match to d2xp2a_
    complexed with ofg

Details for d4ccba_

PDB Entry: 4ccb (more details), 2.03 Å

PDB Description: structure of the human anaplastic lymphoma kinase in complex with 3- ((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl)ethoxy)-5-(5-methyl- 1h- pyrazol-4-yl)pyridin-2-amine
PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d4ccba_:

Sequence, based on SEQRES records: (download)

>d4ccba_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
mardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpiey

Sequence, based on observed residues (ATOM records): (download)

>d4ccba_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnycfagktssisdlkevprknitlirglghgafgevyegqvsplqvavktlpevcseq
deldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqsl
amldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardiyram
lpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdp
pkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpiey

SCOPe Domain Coordinates for d4ccba_:

Click to download the PDB-style file with coordinates for d4ccba_.
(The format of our PDB-style files is described here.)

Timeline for d4ccba_: