SCOPe 2.08: Domain d4itfa_: 4itf A:

Lineage for d4itfa_ (4itf A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d4itfa_: 4itf A: [236143]
   automated match to d3a3zx_
   complexed with tfy

Details for d4itfa_

PDB Entry: 4itf, 2.84 Å

PDB Description: crystal structure of the human vitamin d receptor ligand binding domain complexed with 1alpha,25-dihydroxy-2alpha-[2-(1h-tetrazole-1- yl)ethyl]vitamin d3

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d4itfa_:

Sequence, based on SEQRES records:

>d4itfa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlp
hladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtc
gnqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqd
aalieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqp
ecsmkltplvlevfg

Sequence, based on observed residues (ATOM records):

>d4itfa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgsvtlelsqlsmlphl
adlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcgn
qdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaa
lieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqpec
smkltplvlevfg

Timeline for d4itfa_:

• d4itfa_ first appeared in SCOPe 2.03
  
• d4itfa_ appears in SCOPe 2.07