SCOPe 2.05: Domain d4nvqa_: 4nvq A:

Lineage for d4nvqa_ (4nvq A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.85: beta-clip [51268] (7 superfamilies)
   double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll

4. Superfamily b.85.7: SET domain [82199] (4 families)
   duplication: the core is composed of two structural repeats similar to (circularly permuted) repeats of AFPIII
   also contains a substrate-binding alpha+beta subdomain inserted in the core

5. Family b.85.7.0: automated matches [227191] (1 protein)
   not a true family

6. Protein automated matches [226914] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225158] (11 PDB entries)

8. Domain d4nvqa_: 4nvq A: [236076]
   automated match to d3mo5c_
   complexed with 2od, sah, zn

Details for d4nvqa_

PDB Entry: 4nvq, 2.03 Å

PDB Description: human g9a in complex with inhibitor a-366

PDB Compounds: (A:) Histone-lysine N-methyltransferase EHMT2

SCOPe Domain Sequences for d4nvqa_:

Sequence, based on SEQRES records:

>d4nvqa_ b.85.7.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
irtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhct
cvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsg
ikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdldnkdge
vycidaryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdyg
drfwdikskyftcqcgsekckhsaeaialeqs

Sequence, based on observed residues (ATOM records):

>d4nvqa_ b.85.7.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
irtekiicrdvargyenvpipcvngvdgepcpedykyisencetstmnidrnithlqhct
cvddcsssnclcgqlsircwydkdgrllqefnkiepplifecnqacscwrncknrvvqsg
ikvrlqlyrtakmgwgvralqtipqgtficeyvgelisdaeadvreddsylfdlgevyci
daryygnisrfinhlcdpniipvrvfmlhqdlrfpriaffssrdirtgeelgfdygdrfw
diksyftcqcgsekckhsaeaialeqs

Timeline for d4nvqa_:

• d4nvqa_ first appeared in SCOPe 2.03
  
• d4nvqa_ appears in SCOPe 2.04
  
• d4nvqa_ appears in SCOPe 2.06
  
• d4nvqa_ appears in the current release, SCOPe 2.08