SCOPe 2.08: Domain d4mvhb_: 4mvh B:

Lineage for d4mvhb_ (4mvh B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d4mvhb_: 4mvh B: [236065]
   automated match to d4muwa_
   complexed with 2f5, so4, zn

Details for d4mvhb_

PDB Entry: 4mvh, 2.5 Å

PDB Description: Crystal Structure of PDE10A with Novel Keto-Benzimidazole Inhibitor

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4mvhb_:

Sequence; same for both SEQRES and ATOM records:

>d4mvhb_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvkknyrr
vpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylqkfdhp
laalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgn
rkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegd
emkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsq
wekvirge

Timeline for d4mvhb_:

• d4mvhb_ first appeared in SCOPe 2.03
  
• d4mvhb_ appears in SCOPe 2.07