SCOPe 2.05: Domain d4n7jb_: 4n7j B:

Lineage for d4n7jb_ (4n7j B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.0: automated matches [191651] (1 protein)
   not a true family

6. Protein automated matches [191201] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189525] (14 PDB entries)

8. Domain d4n7jb_: 4n7j B: [235745]
   automated match to d4n5db_
   complexed with 2gq, po4

Details for d4n7jb_

PDB Entry: 4n7j, 1.67 Å

PDB Description: Tailoring Small Molecules for an Allosteric Site on Procaspase-6

PDB Compounds: (B:) Caspase-6

SCOPe Domain Sequences for d4n7jb_:

Sequence, based on SEQRES records:

>d4n7jb_ c.17.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mfdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfn
dlkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkch
slvgkpkifiiqaargnqhdvpvipldvvdnqtekldtnitevdaasvytlpagadflmc
ysvaegyyshretvngswyiqdlcemlgkygssleftelltlvnrkvsqrrvdfckdpsa
igkkqvpcfasmltkklhffpk

Sequence, based on observed residues (ATOM records):

>d4n7jb_ c.17.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mfdpaekykmdhrrrgialifnherffwhltlperrgtcadrdnltrrfsdlgfevkcfn
dlkaeelllkihevstvshadadcfvcvflshgegnhiyaydakieiqtltglfkgdkch
slvgkpkifiiqaargnqtnitevdaasvytlpagadflmcysvaegyyshretvngswy
iqdlcemlgkygssleftelltlvnrkvsqrrvdfckdpsaigkkqvpcfasmltkklhf
fpk

Timeline for d4n7jb_:

• d4n7jb_ first appeared in SCOPe 2.03
  
• d4n7jb_ appears in SCOPe 2.04
  
• d4n7jb_ appears in SCOPe 2.06
  
• d4n7jb_ appears in the current release, SCOPe 2.08