SCOP 1.65: Domain d2hwf1_: 2hwf 1:

Lineage for d2hwf1_ (2hwf 1:)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
   sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
   characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies

4. Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (7 families)

5. Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (9 proteins)
   the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
   there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)

6. Protein Rhinovirus coat proteins [49670] (5 species)

7. Species Human rhinovirus A 1A (HRV-1A) [TaxId:12134] [49673] (4 PDB entries)

8. Domain d2hwf1_: 2hwf 1: [23546]
   complexed with jen

Details for d2hwf1_

PDB Entry: 2hwf, 3.8 Å

PDB Description: a comparison of the anti-rhinoviral drug binding pocket in hrv14 and hrv1a

SCOP Domain Sequences for d2hwf1_:

Sequence; same for both SEQRES and ATOM records:

>d2hwf1_ b.121.4.1 (1:) Rhinovirus coat proteins {Human rhinovirus A 1A (HRV-1A)}
nyidevlnevlvvpnikeshhttsnsaplldaaetghtsnvqpedaietryvitsqtrde
msiesflgrsgcvhisrikvdytdyngqdinftkwkitlqemaqirrkfelftyvrfdse
itlvpciagrgddighivmqymyvppgapipskrndfswqsgtnmsifwqhgqpfprfsi
pflsiasayymfydgydgdntsskygsvvtndmgticsrivtekqklsvvitthiyhkak
htkawcprppravpythshvtnympetgdvttaivrrntitta

Timeline for d2hwf1_:

• d2hwf1_ first appeared (with stable ids) in SCOP 1.55
  
• d2hwf1_ appears in SCOP 1.63
  
• d2hwf1_ appears in SCOP 1.67
  
• d2hwf1_ appears in the current release, SCOPe 2.08