SCOPe 2.05: Domain d4lg4e_: 4lg4 E:

Lineage for d4lg4e_ (4lg4 E:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d4lg4e_: 4lg4 E: [235367]
   automated match to d4lg4a_
   complexed with gol

Details for d4lg4e_

PDB Entry: 4lg4, 2.42 Å

PDB Description: structural basis for autoactivation of human mst2 kinase and its regulation by rassf5

PDB Compounds: (E:) Serine/threonine-protein kinase 3

SCOPe Domain Sequences for d4lg4e_:

Sequence, based on SEQRES records:

>d4lg4e_ d.144.1.0 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sltkqpeevfdvleklgegsygsvfkaihkesgqvvaikqvpvesdlqeiikeisimqqc
dspyvvkyygsyfkntdlwivmeycgagsvsdiirlrnktliedeiatilkstlkgleyl
hfmrkihrnikagnillnteghakladfgvagqltdtmakrntvigtpfwmapeviqeig
yncvadiwslgitsiemaegkppyadihpmraifmiptnppptfrkpelwsddftdfvkk
clvknpeqratatqllqhpfiknakpvsilrdliteameikakrheeqqre

Sequence, based on observed residues (ATOM records):

>d4lg4e_ d.144.1.0 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sltkqpeevfdvleklgsvfkaihkesgqvvaikqvlqeiikeisimqqcdspyvvkyyg
syfkntdlwivmeycgagsvsdiirlrnktliedeiatilkstlkgleylhfmrkihrni
kagnillnteghakladfgvagqltdtvigtpfwmapeviqeigyncvadiwslgitsie
maegkppyadihpmraifmiptnppptfrkpelwsddftdfvkkclvknpeqratatqll
qhpfiknakpvsilrdliteameikakrheeqqre

Timeline for d4lg4e_:

• d4lg4e_ first appeared in SCOPe 2.03
  
• d4lg4e_ appears in SCOPe 2.04
  
• d4lg4e_ appears in SCOPe 2.06
  
• d4lg4e_ appears in the current release, SCOPe 2.08