Lineage for d4kbkd_ (4kbk D:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218626Protein Casein kinase-1, CK1 [56139] (4 species)
    OPK group; CKI subfamily; serine/threonine kinase
  7. 2218632Species Human (Homo sapiens) [TaxId:9606] [224941] (14 PDB entries)
  8. 2218648Domain d4kbkd_: 4kbk D: [235139]
    automated match to d4kbad_
    complexed with 1qg, so4

Details for d4kbkd_

PDB Entry: 4kbk (more details), 2.1 Å

PDB Description: CK1d in complex with (3S)-3-{4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]pyridin-2-yl}morpholine inhibitor
PDB Compounds: (D:) Casein kinase I isoform delta

SCOPe Domain Sequences for d4kbkd_:

Sequence, based on SEQRES records: (download)

>d4kbkd_ d.144.1.7 (D:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqgg
vgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsk
nfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasi
nthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlck
gypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

Sequence, based on observed residues (ATOM records): (download)

>d4kbkd_ d.144.1.7 (D:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigdiylgtdiaageevaiklecpqlhieskiykmmqggvgiptirwcg
aegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsknfihrdvkpd
nflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasinthlgieqsr
rddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlckgypsefatyl
nfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

SCOPe Domain Coordinates for d4kbkd_:

Click to download the PDB-style file with coordinates for d4kbkd_.
(The format of our PDB-style files is described here.)

Timeline for d4kbkd_: