Lineage for d4kb8b_ (4kb8 B:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1433952Protein Casein kinase-1, CK1 [56139] (4 species)
    OPK group; CKI subfamily; serine/threonine kinase
  7. 1433958Species Human (Homo sapiens) [TaxId:9606] [224941] (6 PDB entries)
  8. 1433964Domain d4kb8b_: 4kb8 B: [235132]
    automated match to d4kbad_
    complexed with 1qn, 1qo, so4

Details for d4kb8b_

PDB Entry: 4kb8 (more details), 1.95 Å

PDB Description: ck1d in complex with 1-{4-[3-(4-fluorophenyl)-1-methyl-1h-pyrazol-4-yl]pyridin-2-yl}-n-methylmethanamine ligand
PDB Compounds: (B:) Casein kinase I isoform delta

SCOPe Domain Sequences for d4kb8b_:

Sequence, based on SEQRES records: (download)

>d4kb8b_ d.144.1.7 (B:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecvktkhpqlhieskiykmmqgg
vgiptirwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsk
nfihrdvkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasi
nthlgieqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlck
gypsefatylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

Sequence, based on observed residues (ATOM records): (download)

>d4kb8b_ d.144.1.7 (B:) Casein kinase-1, CK1 {Human (Homo sapiens) [TaxId: 9606]}
lrvgnryrlgrkigsgsfgdiylgtdiaageevaiklecqlhieskiykmmqggvgipti
rwcgaegdynvmvmellgpsledlfnfcsrkfslktvllladqmisrieyihsknfihrd
vkpdnflmglgkkgnlvyiidfglakkyrdarthqhipyrenknltgtaryasinthlgi
eqsrrddleslgyvlmyfnlgslpwqglkaatkrqkyerisekkmstpievlckgypsef
atylnfcrslrfddkpdysylrqlfrnlfhrqgfsydyvfdwnml

SCOPe Domain Coordinates for d4kb8b_:

Click to download the PDB-style file with coordinates for d4kb8b_.
(The format of our PDB-style files is described here.)

Timeline for d4kb8b_: