SCOPe 2.08: Domain d4k4pa_: 4k4p A:

Lineage for d4k4pa_ (4k4p A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (590 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d4k4pa_: 4k4p A: [235097]
   automated match to d4k4qa_
   complexed with 3tl, no3

Details for d4k4pa_

PDB Entry: 4k4p, 2.31 Å

PDB Description: TL-3 inhibited Trp6Ala HIV Protease

PDB Compounds: (A:) hiv-1 protease

SCOPe Domain Sequences for d4k4pa_:

Sequence; same for both SEQRES and ATOM records:

>d4k4pa_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlakrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d4k4pa_:

• d4k4pa_ first appeared in SCOPe 2.03
  
• d4k4pa_ appears in SCOPe 2.07