SCOPe 2.03: Domain d4imya_: 4imy A:

Lineage for d4imya_ (4imy A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d4imya_: 4imy A: [234886]
   Other proteins in same PDB: d4imyb1, d4imyb2
   automated match to d3my1a_
   complexed with amp

Details for d4imya_

PDB Entry: 4imy, 2.94 Å

PDB Description: The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat

PDB Compounds: (A:) Cyclin-dependent kinase 9

SCOPe Domain Sequences for d4imya_:

Sequence, based on SEQRES records:

>d4imya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspynrckgsiylvfdfcehdlagllsnvlvkftlseik
rvmqmllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytn
rvvtlwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgs
itpevwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsd
dalnhdffwsdpmpsdlkgmlst

Sequence, based on observed residues (ATOM records):

>d4imya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkgsiylvfdfcehdlagllsnvlvkftlseikrvmqmlln
glyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytnrvvtlwyr
ppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgsitpevwpn
vdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsddalnhdff
wsdpmpsdlkgmlst

Timeline for d4imya_:

• d4imya_ is new in SCOPe 2.03-stable
  
• d4imya_ appears in SCOPe 2.04
  
• d4imya_ appears in the current release, SCOPe 2.08