SCOPe 2.08: Domain d4he2a_: 4he2 A:

Lineage for d4he2a_ (4he2 A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
   N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet

4. Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families)

5. Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)

6. Protein automated matches [190281] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187709] (50 PDB entries)

8. Domain d4he2a_: 4he2 A: [234643]
   automated match to d4he1a_
   complexed with amp, cl, mg, po3, zn; mutant

Details for d4he2a_

PDB Entry: 4he2, 1.6 Å

PDB Description: crystal structure of human muscle fructose-1,6-bisphosphatase q32r mutant complex with amp

PDB Compounds: (A:) Fructose-1,6-bisphosphatase isozyme 2

SCOPe Domain Sequences for d4he2a_:

Sequence, based on SEQRES records:

>d4he2a_ e.7.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltltryvmekgrqakgtgeltrllnsmltaikaissavrkaglahlygiagsvnvtgdev
kkldvlsnslvinmlqssystcvlvseenkdaiitakekrgkyvvcfdpldgssnidcla
sigtifaiyrktsedepsekdalqcgrnivaagyalygsatlvalstgqgvdlfmldpal
gefvlvekdvkikkkgkiyslnegyakyfdaatteyvqkkkfpedgsapygaryvgsmva
dvhrtlvyggiflypanqkspkgklrllyecnpvayiieqagglattgtqpvldvkpeai
hqrvplilgspedvqeyltcvqknq

Sequence, based on observed residues (ATOM records):

>d4he2a_ e.7.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltltryvmekgrqakgtgeltrllnsmltaikaissavrkaglakldvlsnslvinmlqs
systcvlvseenkdaiitakekrgkyvvcfdpldgssnidclasigtifaiyrktsedep
sekdalqcgrnivaagyalygsatlvalstgqgvdlfmldpalgefvlvekdvkikkkgk
iyslnegyakyfdaatteyvqkkkfpedgsapygaryvgsmvadvhrtlvyggiflypan
qkspkgklrllyecnpvayiieqagglattgtqpvldvkpeaihqrvplilgspedvqey
ltcvqknq

Timeline for d4he2a_:

• d4he2a_ first appeared in SCOPe 2.03
  
• d4he2a_ appears in SCOPe 2.07