Lineage for d4h6ta_ (4h6t A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056594Protein Thrombin [50531] (2 species)
  7. 2056630Species Human (Homo sapiens) [TaxId:9606] [50532] (170 PDB entries)
    Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620
  8. 2056797Domain d4h6ta_: 4h6t A: [234623]
    automated match to d3k65b_
    complexed with po4; mutant

Details for d4h6ta_

PDB Entry: 4h6t (more details), 2.4 Å

PDB Description: Crystal structure of prethrombin-2 mutant E14eA/D14lA/E18A/S195A
PDB Compounds: (A:) Prothrombin

SCOPe Domain Sequences for d4h6ta_:

Sequence, based on SEQRES records: (download)

>d4h6ta_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
tseyqtffnprtfgsgeadcglrplfekksledkterallesyiagrivagsdaeigmsp
wqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryer
niekismlekiyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqag
ykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpd
egkrgdacegdaggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkv
idqfge

Sequence, based on observed residues (ATOM records): (download)

>d4h6ta_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
tseyqtffnprtfgsgeadcglrplfekksledkterallesyiagrivagsdaeigmsp
wqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryer
niekismlekiyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqag
ykgrvtgwgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdag
gpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

SCOPe Domain Coordinates for d4h6ta_:

Click to download the PDB-style file with coordinates for d4h6ta_.
(The format of our PDB-style files is described here.)

Timeline for d4h6ta_: