Lineage for d4grof_ (4gro F:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1915130Fold d.80: Tautomerase/MIF [55330] (1 superfamily)
    (beta-alpha-beta)2; 2 layers: alpha/beta; mixed beta-sheet
    generally forms trimers with three closely packed beta-sheets
  4. 1915131Superfamily d.80.1: Tautomerase/MIF [55331] (7 families) (S)
  5. 1915295Family d.80.1.3: MIF-related [55339] (2 proteins)
    automatically mapped to Pfam PF01187
  6. 1915312Protein Microphage migration inhibition factor (MIF) [55340] (7 species)
    synonym: glycosylation-inhibiting factor (GIF)
  7. 1915318Species Human (Homo sapiens) [TaxId:9606] [55341] (59 PDB entries)
  8. 1915456Domain d4grof_: 4gro F: [234501]
    automated match to d4grod_
    complexed with cl; mutant

Details for d4grof_

PDB Entry: 4gro (more details), 2 Å

PDB Description: crystallographic and biological characterization of n- and c- terminus mutants of human mif
PDB Compounds: (F:) macrophage migration inhibitory factor

SCOPe Domain Sequences for d4grof_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4grof_ d.80.1.3 (F:) Microphage migration inhibition factor (MIF) {Human (Homo sapiens) [TaxId: 9606]}
paaamfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepca
lcslhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa

SCOPe Domain Coordinates for d4grof_:

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Timeline for d4grof_: