Lineage for d4gb2b_ (4gb2 B:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2391025Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2391026Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2391027Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2391043Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2391226Species Human immunodeficiency virus type 1 (bru isolate) [TaxId:11686] [194276] (21 PDB entries)
  8. 2391258Domain d4gb2b_: 4gb2 B: [234459]
    automated match to d1mrwa_
    complexed with 0lq, cl, gol; mutant

Details for d4gb2b_

PDB Entry: 4gb2 (more details), 1.79 Å

PDB Description: HIV-1 protease (mutant Q7K L33I L63I) in complex with a bicyclic pyrrolidine inhibitor
PDB Compounds: (B:) Gag-Pol polyprotein

SCOPe Domain Sequences for d4gb2b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4gb2b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 (bru isolate) [TaxId: 11686]}

SCOPe Domain Coordinates for d4gb2b_:

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Timeline for d4gb2b_: